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Article

Control of the sperm-oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3' untranslated region.

Nature - 24 Jan 1991

Ahringer J, Kimble J

Abstract excerpt

In the Caenorhabditis elegans hermaphrodite germ line, sperm and then oocytes are made from a common pool of germ-cell precursors. The decision to differentiate as a sperm or an oocyte is regulated by the sex-determining gene, fem-3. Expression of fem-3 in the hermaphrodite germ line directs spermatogenesis and must be negatively regulated to allow the switch to oogenesis. In adult hermaphrodites (which are...

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PMID: 1702880
DOI: 10.1038/349346a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Control of the sperm-oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3' untranslated region.PMID 1702880Read ↗

Repression by the 3' UTR of fem-3, a sex-determining gene, relies on a ubiquitous mog-dependent control in Caenorhabditis elegans.Semantic proximity Read ↗

More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans.Semantic proximity Read ↗

The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans.Semantic proximity Read ↗

The hermaphrodite sperm/oocyte switch requires the Caenorhabditis elegans homologs of PRP2 and PRP22.Semantic proximity Read ↗

The Caenorhabditis elegans sex determination gene mog-1 encodes a member of the DEAH-Box protein family.Semantic proximity Read ↗

GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans.Semantic proximity Read ↗

GLS-1, a novel P granule component, modulates a network of conserved RNA regulators to influence germ cell fate decisions.Semantic proximity Read ↗

A protein.protein interaction platform involved in recruitment of GLD-3 to the FBF.fem-3 mRNA complex.Semantic proximity Read ↗

A male-specific 3'-UTR regulates the steady-state level of the exuperantia mRNA during spermatogenesis in Drosophila.Semantic proximity Read ↗

The <i>mex</i> -3 3’ untranslated region is essential for reproduction during temperature stressSemantic proximity Read ↗

Translational regulators maintain totipotency in the Caenorhabditis elegans germline.Semantic proximity Read ↗

Multiple RNA regulatory pathways coordinate the activity and expression pattern of a conserved germline RNA-binding proteinSemantic proximity Read ↗

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