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Article

Control of the sperm-oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3' untranslated region.

Nature - 24 Jan 1991

Ahringer J, Kimble J

Abstract excerpt

In the Caenorhabditis elegans hermaphrodite germ line, sperm and then oocytes are made from a common pool of germ-cell precursors. The decision to differentiate as a sperm or an oocyte is regulated by the sex-determining gene, fem-3. Expression of fem-3 in the hermaphrodite germ line directs sper...

Topics

Animals
Base Sequence
Caenorhabditis
Cell Differentiation
Disorders of Sex Development
Gene Expression Regulation
Male
Molecular Sequence Data
Mutation
Oocytes
Oogenesis
Plasmids
Protein Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA

Sex Determination Analysis

Spermatogenesis

Spermatozoa

Transformation, Genetic

Source

Identifiers

PMID: 1702880
DOI: 10.1038/349346a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1702880-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Click a neighbor to travelStep 1 · 12 closest

Control of the sperm-oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3' untranslated region.PMID 1702880Read ↗

Repression by the 3' UTR of fem-3, a sex-determining gene, relies on a ubiquitous mog-dependent control in Caenorhabditis elegans.Semantic proximity Read ↗

More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans.Semantic proximity Read ↗

The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans.Semantic proximity Read ↗

The hermaphrodite sperm/oocyte switch requires the Caenorhabditis elegans homologs of PRP2 and PRP22.Semantic proximity Read ↗

The Caenorhabditis elegans sex determination gene mog-1 encodes a member of the DEAH-Box protein family.Semantic proximity Read ↗

GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans.Semantic proximity Read ↗

GLS-1, a novel P granule component, modulates a network of conserved RNA regulators to influence germ cell fate decisions.Semantic proximity Read ↗

A protein.protein interaction platform involved in recruitment of GLD-3 to the FBF.fem-3 mRNA complex.Semantic proximity Read ↗

A male-specific 3'-UTR regulates the steady-state level of the exuperantia mRNA during spermatogenesis in Drosophila.Semantic proximity Read ↗

The <i>mex</i> -3 3’ untranslated region is essential for reproduction during temperature stressSemantic proximity Read ↗

Translational regulators maintain totipotency in the Caenorhabditis elegans germline.Semantic proximity Read ↗

Multiple RNA regulatory pathways coordinate the activity and expression pattern of a conserved germline RNA-binding proteinSemantic proximity Read ↗

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