Article
A deletion defining a common Asian lineage of Mycobacterium tuberculosis associates with immune subversion.
Proceedings of the National Academy of Sciences of the United States of America - 17 Oct 2006
Newton Sandra M, Smith Rebecca J, Wilkinson Katalin A, Nicol Mark P, Garton Natalie J, Staples Karl J, Stewart Graham R, Wain John R, Martineau Adrian R, Fandrich Sarah, Smallie Timothy, Foxwell Brian, Al-Obaidi Ahmed, Shafi Jamila, Rajakumar Kumar, Kampmann Beate, Andrew Peter W, Ziegler-Heitbrock Loems, Barer Michael R, Wilkinson Robert J
Abstract excerpt
Six major lineages of Mycobacterium tuberculosis appear preferentially transmitted amongst distinct ethnic groups. We identified a deletion affecting Rv1519 in CH, a strain isolated from a large outbreak in Leicester U.K., that coincidentally defines the East African-Indian lineage matching a maj...
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