Whole-arm translocations between chromosome 1 and acrocentric G chromosomes are associated with a poor prognosis for spermatogenesis: two new cases and review of the literature.

Abstract excerpt

OBJECTIVE: To analyze unusual translocations involving a chromosome 1 whole arm and an acrocentric G chromosome p arm found in two men with azoospermia. DESIGN: Case report with review of the scientific literature. SETTING: Cytogenetics department. PATIENT(S): Two men with azoospermia and normal hormonal levels. INTERVENTIONS(S): Peripheral blood lymphocytes were obtained for karyotype, and metaphases were...

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