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Article

Patients with abnormal sperm parameters have an increased sex chromosome aneuploidy rate in peripheral leukocytes

5 May 2005

Abstract excerpt

BACKGROUND: Patients with oligoasthenoteratozoospermia (OAT) and normal karyotypes have an increased sperm aneuploidy rate. This may be due to an altered intratesticular environment that affects the chromosomal segregation mechanism(s). Alternatively, it may be due to a generalized meiotic and mitotic abnormality. In this case, patients with abnormal spermatogenesis should also have an increased somatic cell...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 15878928
DOI: 10.1093/humrep/dei036

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