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Article

Apolipoprotein E polymorphism and dendritic shape in hippocampal interneurons.

Neurobiology of aging - 1 May 2007

Schönheit Bärbel, Glöckner Frauke, Ohm Thomas G

Abstract excerpt

The apolipoprotein E genetic polymorphism exerts a well described influence on Alzheimer's disease (AD) risk, although the pathogenetic mechanism is still not clear. Increasing evidence points to a diminished neuroplasticity in apolipoprotein E varepsilon4-allele carriers. But, alternatively or additionally, developmental differences in dendritic geometry may be associated with the polymorphism. We...

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PMID: 17023092
DOI: 10.1016/j.neurobiolaging.2006.03.016

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