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Article

Molecular definition of an allelic series of mutations disrupting the mouse Lmx1a (dreher) gene.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2006

Chizhikov Victor, Steshina Ekaterina, Roberts Richard, Ilkin Yesim, Washburn Linda, Millen Kathleen J

Abstract excerpt

Mice homozygous for the dreher (dr) mutation are characterized by pigmentation and skeletal abnormalities and striking behavioral phenotypes, including ataxia, vestibular deficits, and hyperactivity. The ataxia is associated with a cerebellar malformation that is remarkably similar to human Dandy-Walker malformation. Previously, positional cloning identified mutations in LIM homeobox transcription factor 1 alpha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17019651
DOI: 10.1007/s00335-006-0033-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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