Article
HLA markers in familial Lichen sclerosus.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG - 1 Oct 2006
Aslanian Flavia M N P, Marques Maria Teresa Q, Matos Haroldo J, Pontes Luciane F S, Porto Luis Cristóvão S, Azevedo Lucia M S, Filgueira Absalom L
Abstract excerpt
BACKGROUND: Lichen sclerosus (LS) has been identified with increased frequency in families,often associated with HLA markers, mainly DQ7. A genetic co-etiology seems likely in this setting. Moreover, there is an association of LS with autoimmune disorders, such as the presence of anti-thyroid peroxidase autoantibodies (anti-TPO), a hallmark of autoimmune thyroid diseases. PATIENTS AND METHODS: In 3 families...
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