Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sustained cell proliferation of renal epithelial cells in mice with inv mutation.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Oct 2006

Sugiyama Noriyuki, Yokoyama Takahiko

Abstract excerpt

A tubule system is an important component of the nephron, which is the structural and functional unit of the kidney. Expansion of renal tubules results in renal cysts. Hereditary forms of renal cystic diseases suggest that tubular size is determined genetically. The inv was discovered as a mutant with renal cysts and situs inversus. Inv/inv, inv deltaC::GFP (inv deltaC) mouse was created by the introduction of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Cell Cycle Proteins
Share to Epithelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Growth Substances

Share to Homozygote

Share to Kidney Tubules

Share to Mice, Mutant Strains

Share to Polycystic Kidney Diseases

Source

Identifiers

PMID: 16999740
DOI: 10.1111/j.1365-2443.2006.01011.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sustained cell proliferation of renal epithelial cells in mice with inv mutation.PMID 16999740Read ↗

Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.Semantic proximity Read ↗

The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice.Semantic proximity Read ↗

Renal cysts of inv/inv mice resemble early infantile nephronophthisis.Semantic proximity Read ↗

The Inv compartment of renal cilia is an intraciliary signal-activating center to phosphorylate ANKS6.Semantic proximity Read ↗

Proliferation control of kidney interstitial cellsSemantic proximity Read ↗

Structural basis of the Inv compartment and ciliary abnormalities in Inv/nphp2 mutant mice.Semantic proximity Read ↗

Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary ciliaSemantic proximity Read ↗

Localization of Inv in a distinctive intraciliary compartment requires the C-terminal ninein-homolog-containing regionSemantic proximity Read ↗

Inversin forms a complex with catenins and N-cadherin in polarized epithelial cells.Semantic proximity Read ↗

Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease.Semantic proximity Read ↗

Relationship between sodium-dependent phosphate transporter (NaPi-IIc) function and cellular vacuole formation in opossum kidney cells.Semantic proximity Read ↗

Cystic Renal Neoplasia Following Conditional Inactivation of Apc in Mouse Renal Tubular EpitheliumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.