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Article

Analysis of p53 and Bak gene mutations in lymphoproliferative disorders developing in rheumatoid arthritis.

Journal of cancer research and clinical oncology - 1 Feb 2007

Xu Jing-Xian, Hoshida Yoshihiko, Hongyo Tadashi, Sasaki Toru, Miyazato Hajime, Tomita Yasuhiko, Aozasa Katsuyuki

Abstract excerpt

PURPOSE: Individuals affected by rheumatoid arthritis (RA) occasionally develop lymphoproliferative disorders (RA-LPD). To study the molecular changes underscoring the RA-LPD, mutations of p53 and Bak gene were analyzed in RA-LPD with (MTX-LPD) or without methotrexate treatment for RA (non-MTX-LPD). METHODS: Histology and immunophenotype were immunohistochemically examined in 32 cases of MTX-LPD and 21 of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to bcl-2 Homologous Antagonist-Killer Protein

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Identifiers

PMID: 16988840
DOI: 10.1007/s00432-006-0152-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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