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Article

Optimization of the delivery of heterologous proteins by the Salmonella enterica serovar Typhimurium type III secretion system for vaccine development.

Infection and immunity - 1 Oct 2006

Chen Li-Mei, Briones Gabriel, Donis Ruben O, Galán Jorge E

Abstract excerpt

Type III protein secretion systems, which are organelles with the capacity to deliver bacterial proteins into host cells, have been adapted to deliver heterologous antigens for vaccine development. A limitation of these antigen delivery systems is that some proteins are not amenable to secretion through this pathway. We show here that proteins from the simian and human immunodeficiency viruses that are not...

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Identifiers

PMID: 16988261
DOI: 10.1128/IAI.00375-06
PMCID: PMC1594939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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