Article
Major role for FeoB in Campylobacter jejuni ferrous iron acquisition, gut colonization, and intracellular survival.
Infection and immunity - 1 Oct 2006
Naikare Hemant, Palyada Kiran, Panciera Roger, Marlow Denver, Stintzi Alain
Abstract excerpt
To assess the importance of ferrous iron acquisition in Campylobacter physiology and pathogenesis, we disrupted and characterized the Fe2+ iron transporter, FeoB, in Campylobacter jejuni NCTC 11168, 81-176, and ATCC 43431. The feoB mutant was significantly affected in its ability to transport 55Fe2+. It accumulated half the amount of iron than the wild-type strain during growth in an iron-containing medium. The...
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