Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Four primary malignancies successively occurred in a BRCA2 mutation carrier: a case report.

Cancer investigation - 1 Oct 2006

Fruscalzo A, Damante G, Calcagno A, Di Loreto C, Marchesoni D

Abstract excerpt

Carriers of BRCA2 germline mutation have a significantly increased lifetime risk of breast and ovarian cancer compared to non carriers. Several other carcinomas seem to be associated with BRCA2 mutations: pancreas, prostate, larynx, gallbladder, bile duct cancer, and malignant melanoma. We described a case of a 67-year-old BRCA2 mutation carrier of Caucasian, non-Jewish, ethnic origin who successively developed 4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA2 Protein
Share to Carcinoma, Ductal, Breast
Share to Cystadenocarcinoma, Serous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Neoplasms, Multiple Primary

Share to Ovarian Neoplasms

Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 16982466
DOI: 10.1080/07357900600894872

Genes

BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Four primary malignancies successively occurred in a BRCA2 mutation carrier: a case report.PMID 16982466Read ↗

Three primary malignancies related to BRCA mutation successively occurring in a BRCA1 185delAG mutation carrier.Semantic proximity Read ↗

Concomitant BRCA1 and BRCA2 gene mutations in an Ashkenazi Jewish woman with primary breast and ovarian cancer.Semantic proximity Read ↗

First description of a double heterozygosity for BRCA1 and BRCA2 pathogenic variants in a French metastatic breast cancer patient: A case report.Semantic proximity Read ↗

Selective loss of heterozygosity in multiple breast cancers from a carrier of mutations in both BRCA1 and BRCA2.Semantic proximity Read ↗

Cancer in Jews: introduction and overview.Semantic proximity Read ↗

A case report of triple primary malignant tumors including breast,cervical and thyroid cancers with CHEK2 and PIK3CA mutationSemantic proximity Read ↗

Frequency of BRCA mutations in primary peritoneal carcinoma in Israeli Jewish women.Semantic proximity Read ↗

Second primary breast cancer in BRCA1 and BRCA2 mutation carriers: 10-year cumulative incidence in the Breast Cancer Family Registry.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.