Article
Herpes simplex virus encephalitis in human UNC-93B deficiency.
Science (New York, N.Y.) - 13 Oct 2006
Casrouge Armanda, Zhang Shen-Ying, Eidenschenk Céline, Jouanguy Emmanuelle, Puel Anne, Yang Kun, Alcais Alexandre, Picard Capucine, Mahfoufi Nora, Nicolas Nathalie, Lorenzo Lazaro, Plancoulaine Sabine, Sénéchal Brigitte, Geissmann Frédéric, Tabeta Koichi, Hoebe Kasper, Du Xin, Miller Richard L, Héron Bénédicte, Mignot Cyril, de Villemeur Thierry Billette, Lebon Pierre, Dulac Olivier, Rozenberg Flore, Beutler Bruce, Tardieu Marc, Abel Laurent, Casanova Jean-Laurent
Abstract excerpt
Herpes simplex virus-1 (HSV-1) encephalitis (HSE) is the most common form of sporadic viral encephalitis in western countries. Its pathogenesis remains unclear, as it affects otherwise healthy patients and only a small minority of HSV-1-infected individuals. Here, we elucidate a genetic etiology...
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