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Article

Resistance to alpha/beta interferon is a determinant of West Nile virus replication fitness and virulence.

Journal of virology - 1 Oct 2006

Keller Brian C, Fredericksen Brenda L, Samuel Melanie A, Mock Richard E, Mason Peter W, Diamond Michael S, Gale Michael

Abstract excerpt

The emergence of West Nile virus (WNV) in the Western Hemisphere is marked by the spread of pathogenic lineage I strains, which differ from typically avirulent lineage II strains. To begin to understand the virus-host interactions that may influence the phenotypic properties of divergent lineage...

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Identifiers

PMID: 16973548
DOI: 10.1128/JVI.00768-06
PMCID: PMC1617238

Genes

STAT1
STAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16973548-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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