Article
Association of estrogen receptor alpha gene polymorphisms and lifestyle factors with calcaneal quantitative ultrasound and osteoporosis in postmenopausal Vietnamese women.
Journal of human genetics - 1 Jan 2006
Binh Tran Quang, Shinka Toshikatsu, Khan Nguyen Cong, Hien Vu Thi Thu, Lam Nguyen Thi, Mai Le Bach, Nakano Takuro, Sei Masako, Yamamoto Shigeru, Nakamori Masayo, Nakahori Yutaka
Abstract excerpt
Genetic and lifestyle factors are important in the pathogenesis of osteoporosis. We investigated the relationships of PvuII and XbaI polymorphisms of the estrogen receptor alpha (ER-alpha) gene, lifestyle factors with speed of sound at the calcaneus (calcaneal SOS) and osteoporosis in a population-based study of 140 healthy postmenopausal women. By an analysis of covariates, women with higher copies of P or X...
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