Article
A fluoroorotic acid-resistant mutant of Arabidopsis defective in the uptake of uracil.
Journal of experimental botany - 1 Jan 2006
Mourad George S, Snook Bryan M, Prabhakar Joshua T, Mansfield Tyler A, Schultes Neil P
Abstract excerpt
A fluoroorotic acid (FOA)-resistant mutant of Arabidopsis thaliana was isolated by screening M2 populations of ethyl methane sulphonate (EMS)-mutagenized Columbia seed. FOA resistance was due to a nuclear recessive gene, for1-1, which locates to a 519 kb region in chromosome 5. Assays of key regulatory enzymes in de novo pyrimidine synthesis (uridine monophosphate synthase) and salvage biochemistry (thymidine...
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