Article
UPS1 and UPS2 from Arabidopsis mediate high affinity transport of uracil and 5-fluorouracil.
The Journal of biological chemistry - 22 Oct 2004
Schmidt Anja, Su Yan-Hua, Kunze Reinhard, Warner Susan, Hewitt Matthew, Slocum Robert D, Ludewig Uwe, Frommer Wolf B, Desimone Marcelo
Abstract excerpt
Salvage pathways play an important role in providing nucleobases to cells, which are unable to synthesize sufficient amounts for their needs. Cellular uptake systems for pyrimidines have been described, but in higher eukaryotes, transporters for thymine and uracil have not been identified. Two plant transporters, AtUPS1 and PvUPS1, were recently identified as transporters for allantoin in Arabidopsis and French...
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