Article
Arteries define the position of the thyroid gland during its developmental relocalisation.
Development (Cambridge, England) - 1 Oct 2006
Alt Burkhard, Elsalini Osama A, Schrumpf Pamela, Haufs Nele, Lawson Nathan D, Schwabe Georg C, Mundlos Stefan, Grüters Annette, Krude Heiko, Rohr Klaus B
Abstract excerpt
During vertebrate development, the thyroid gland undergoes a unique relocalisation from its site of induction to a distant species-specific position in the cervical mesenchyme. We have analysed thyroid morphogenesis in wild-type and mutant zebrafish and mice, and find that localisation of growing thyroid tissue along the anteroposterior axis in zebrafish is linked to the development of the ventral aorta. In...
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