Article
[New alloantisera to antigenic determinant I--J, their specificity and effect on the course of tuberculous infection in mice].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 May 1990
Batridinova Z M, Vakhidova G A, Moroz A M, Apt A S
Abstract excerpt
Preparations of anti-I--J alloantisera with higher activity were obtained by a new method, based on induction of expression of the I--J determinant in donor suppressor cells, immunization of mice with such cells, and subsequent elimination of contaminating anti-idiotypic antibodies from antisera by their adsorption on the cells of the recipient murine strain sharing induced idiotype with the donor cells. After...
Topics
- Alleles
- Animals
- Drug Evaluation, Preclinical
- Epitopes
- Genotype
- Immune Sera
- Immune Tolerance
- Immunity, Cellular
- Immunization
- Immunization, Passive
- Isoantibodies