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T-cell responses to peptide fragments of the BK virus T antigen: implications for cross-reactivity of immune response to JC virus

8 Sept 2006

Abstract excerpt

Infection with BK virus (BKV) induces both humoral and cellular immunity, but the viral antigens of T-antigen (T-ag) stimulating T-cell responses are largely unknown. To identify BKV-specific T cells in healthy individuals, peripheral blood lymphocytes were cultured with autologous dendritic cells (DCs) loaded with BKV lysate and T cells were screened for intracellular gamma interferon production after...

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PMID: 16963754
DOI: 10.1099/vir.0.82094-0

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