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Article

Inhibition of inflammatory response in transgenic fat-1 mice on a calorie-restricted diet.

Biochemical and biophysical research communications - 27 Oct 2006

Bhattacharya Arunabh, Chandrasekar Bysani, Rahman Md Mizanur, Banu Jameela, Kang Jing X, Fernandes Gabriel

Abstract excerpt

Both n-3 fatty acids (n-3 FA) and calorie-restriction (CR) exert anti-inflammatory effects in animal models of autoimmunity and inflammation. In the present study we investigated the synergistic anti-inflammatory effects of n-3 FA and CR on LPS-mediated inflammatory responses using fat-1 transgenic mice that generate n-3 FA endogenously. Wild-type (WT) and fat-1 mice were maintained on ad libitum (AL) or CR (40%...

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PMID: 16962071
DOI: 10.1016/j.bbrc.2006.08.093

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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