Article
Gene transposition as a cause of hybrid sterility in Drosophila.
Science (New York, N.Y.) - 8 Sept 2006
Masly John P, Jones Corbin D, Noor Mohamed A F, Locke John, Orr H Allen
Abstract excerpt
We describe reproductive isolation caused by a gene transposition. In certain Drosophila melanogaster-D. simulans hybrids, hybrid male sterility is caused by the lack of a single-copy gene essential for male fertility, JYAlpha. This gene is located on the fourth chromosome of D. melanogaster but on the third chromosome of D. simulans. Genomic and molecular analyses show that JYAlpha transposed to the third...
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