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Article

An essential cell cycle regulation gene causes hybrid inviability in Drosophila.

Science (New York, N.Y.) - 18 Dec 2015

Phadnis Nitin, Baker EmilyClare P, Cooper Jacob C, Frizzell Kimberly A, Hsieh Emily, de la Cruz Aida Flor A, Shendure Jay, Kitzman Jacob O, Malik Harmit S

Abstract excerpt

Speciation, the process by which new biological species arise, involves the evolution of reproductive barriers, such as hybrid sterility or inviability between populations. However, identifying hybrid incompatibility genes remains a key obstacle in understanding the molecular basis of reproductive isolation. We devised a genomic screen, which identified a cell cycle-regulation gene as the cause of male...

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Identifiers

PMID: 26680200
DOI: 10.1126/science.aac7504
PMCID: PMC4703311

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