Article
Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27.
The EMBO journal - 4 Oct 2006
Schubert Daniel, Primavesi Lucia, Bishopp Anthony, Roberts Gethin, Doonan John, Jenuwein Thomas, Goodrich Justin
Abstract excerpt
The plant Polycomb-group (Pc-G) protein CURLY LEAF (CLF) is required to repress targets such as AGAMOUS (AG) and SHOOTMERISTEMLESS (STM). Using chromatin immunoprecipitation, we identify AG and STM as direct targets for CLF and show that they carry a characteristic epigenetic signature of dispersed histone H3 lysine 27 trimethylation (H3K27me3) and localised H3K27me2 methylation. H3K27 methylation is present...
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