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Article

A homologue of the breast cancer-associated gene BARD1 is involved in DNA repair in plants.

The EMBO journal - 20 Sept 2006

Reidt Wim, Wurz Rebecca, Wanieck Kristina, Chu Hoang Ha, Puchta Holger

Abstract excerpt

hBRCA1 and hBARD1 are tumor suppressor proteins that are involved as heterodimer via ubiquitinylation in many cellular processes, such as DNA repair. Loss of BRCA1 or BARD1 results in early embryonic lethality and chromosomal instability. The Arabidopsis genome carries a BRCA1 homologue, and we w...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16957774
DOI: 10.1038/sj.emboj.7601313
PMCID: PMC1570427

Genes

BARD1
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-16957774-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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A homologue of the breast cancer-associated gene BARD1 is involved in DNA repair in plants.PMID 16957774Read ↗

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Functional consequences of a rare missense BARD1 c.403G>A germline mutation identified in a triple-negative breast cancer patient.Semantic proximity Read ↗

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation.Semantic proximity Read ↗

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