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Article

Misregulation of sex-lethal and disruption of male-specific lethal complex localization in Drosophila species hybrids.

Genetics - 1 Nov 2006

Pal Bhadra Manika, Bhadra Utpal, Birchler James A

Abstract excerpt

A major model system for the study of evolutionary divergence between closely related species has been the unisexual lethality resulting from reciprocal crosses of Drosophila melanogaster and D. simulans. Sex-lethal (Sxl), a critical gene for sex determination, is misregulated in these hybrids. In hybrid males from D. melanogaster mothers, there is an abnormal expression of Sxl and a failure of localization of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16951071
DOI: 10.1534/genetics.106.060541
PMCID: PMC1667077

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Source receipt: pubmed, retrieved 7 Sept 2026.

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