Article
Amylin S20G mutation in Mexican population.
Diabetes research and clinical practice - 1 Apr 2007
Garcia-Gonzalez Claudia Lorena, Montoya-Fuentes Hector, Padilla-Rosas Miguel, Sanchez-Corona Jose
Abstract excerpt
Diabetes Mellitus type 2 (DM2) is a group of metabolic disorders characterized by defective insulin action or secretion or both with a 10.6% incidence in Mexican Mestizo population, DM2 is also classified within the localized misfolding diseases due to the amyloid pancreatic deposits found in 90% of the DM2 necropsies. The pancreatic amyloid main component is a protein known as human islet amyloid polypeptide...
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