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Article

The antigenic structure of HBsAg: study of the d/y subtype determinant by chemical modification and site directed mutagenesis.

Molecular immunology - 1 May 1990

Guerrero E, Swenson P D, Hu P S, Peterson D L

Abstract excerpt

Lysine residue 122 of the major protein of HBsAg/adw has been shown previously to be involved in the d subtype determinant. We demonstrate here that the corresponding residue of the HBsAg/ayw, arginine 122, does not play such a critical role the y site of this antigen subtype. Thus, conversion by site directed mutagenesis of arginine 122 to lysine 122 in HBsAg/ayw does not result in the loss of y activity nor...

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Identifiers

PMID: 1694958
DOI: 10.1016/0161-5890(90)90168-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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