Article
Establishment of rat endometrial cell lines by retroviral mediated transfer of immortalizing and transforming oncogenes.
Oncogene - 1 Jun 1990
Wiehle R D, Helftenbein G, Land H, Neumann K, Beato M
Abstract excerpt
To study hormone responsive genes in differentiated epithelial cells and as a model for endometrial carcinoma, lines were established from primary rat endometrial cells by infection with replication-defective retroviruses carrying oncogenes and the selectable gene neo. The initial step involved i...
Topics
- Alkaline Phosphatase
- Animals
- Biomarkers, Tumor
- Cell Line
- Cell Transformation, Viral
- Endometrium
- Female
- Immunohistochemistry
- Keratins
- Oncogene Proteins, Viral
- Phenotype
- Rats
- Receptors, Estrogen
- Receptors, Glucocorticoid
- Receptors, Progesterone
- Retroviridae
- Retroviridae Proteins, Oncogenic
- Vimentin