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Article

Establishment of rat endometrial cell lines by retroviral mediated transfer of immortalizing and transforming oncogenes.

Oncogene - 1 Jun 1990

Wiehle R D, Helftenbein G, Land H, Neumann K, Beato M

Abstract excerpt

To study hormone responsive genes in differentiated epithelial cells and as a model for endometrial carcinoma, lines were established from primary rat endometrial cells by infection with replication-defective retroviruses carrying oncogenes and the selectable gene neo. The initial step involved immortalization through the large T antigen of SV40 to generate a line we designate RENT4, or with the E1a gene of...

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PMID: 1694289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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