Article
Reelin gene polymorphisms in the Indian population: a possible paternal 5'UTR-CGG-repeat-allele effect on autism.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2007
Dutta Shruti, Guhathakurta Subhrangshu, Sinha Swagata, Chatterjee Anindita, Ahmed Shabina, Ghosh Saurabh, Gangopadhyay Prasanta K, Singh Manoranjan, Usha Rajamma
Abstract excerpt
Autism is a neurodevelopmental disorder with high heritability factor and the reelin gene, which codes for an extracellular matrix protein involved with neuronal migration and lamination is being investigated as a positional and functional candidate gene for autism. It is located on chromosome 7q22 within the autism susceptible locus (AUTS1); identified in earlier genome scans and several investigations have been...
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