Article
Population-based and family-based association study of 5'UTR polymorphism of the reelin gene and schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Aug 2005
Goldberger Céline, Gourion David, Leroy Sophie, Schürhoff Franck, Bourdel Marie-Chantal, Leboyer Marion, Krebs Marie-Odile
Abstract excerpt
Reelin is a glycoprotein involved in the migration and positioning of proliferating neurons and synaptic connectivity during neurodevelopment. It may also modulate neuronal plasticity throughout life. Therefore, the reelin gene is a candidate gene for schizophrenia. We examined the association of the CGG repeat polymorphism in the 5'-untranslated region of the reelin gene with schizophrenia in 266 unrelated...
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