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Article

The challenge of Down syndrome.

Trends in molecular medicine - 1 Oct 2006

Antonarakis Stylianos E, Epstein Charles J

Abstract excerpt

Down syndrome (DS) has been recognized as a clinical entity for about 150 years, but it is only recently that there has been hope for the possibility to understand its pathogenesis and to use this information to devise approaches for the prevention and treatment of its numerous features. The earlier pessimism was due to several reasons, including: (i) the nature of the genetic defect that leads to the syndrome;...

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Identifiers

PMID: 16935027
DOI: 10.1016/j.molmed.2006.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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