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Article

Opposing Roles of Mitogenic and Stress Signaling Pathways in the Induction of Cancer Dormancy

2 Aug 2006

Abstract excerpt

Cancer dormancy is a poorly understood stage of cancer progression. However, the ability to control this step of the disease offers novel therapeutic opportunities. Here we summarize recent findings that implicate the extracellular matrix and adhesion receptor signaling in the escape or induction of tumor dormancy. We further review evidence suggesting that imbalances in the activity ratio of ERK to p38 signaling...

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PMID: 16929185
DOI: 10.4161/cc.5.16.3109

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