Article
[Association of single nucleotide polymorphisms and haplotypes in DNA repair gene XRCC1 with susceptibility of breast cancer].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 1 Jul 2006
Jin Ming-juan, Chen Kun, Zhang Shuang-shuang, Zhang Yong-jing, Ren Yan-jun, Xu Hong, Yao Kai-yan, Li Qi-long, Ma Xin-yuan
Abstract excerpt
OBJECTIVE: To examine the contribution of the three most common single nucleotide polymorphisms (SNPs) in XRCC1 gene, C26304T, G27466A and G28152A, to susceptibility of breast cancer in Chinese Han population. METHODS: In this population-based case control study, 84 cases with breast cancer and 252 controls, matched to the cases in terms of habitation and age (5 years), were genotyped for the XRCC1 C26304T,...
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