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Article

Adult hippocampus derived soluble factors induce a neuronal-like phenotype in mesenchymal stem cells.

Neuroscience letters - 2 Oct 2006

Rivera Francisco J, Sierralta Walter D, Minguell Jose J, Aigner Ludwig

Abstract excerpt

Bone marrow-derived mesenchymal stem cells (MSCs) are not restricted in their differentiation fate to cells of the mesenchymal lineage. They acquire a neural phenotype in vitro and in vivo after transplantation in the central nervous system. Here we investigated whether soluble factors derived from different brain regions are sufficient to induce a neuronal phenotype in MSCs. We incubated bone marrow-derived MSCs...

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Identifiers

PMID: 16916578
DOI: 10.1016/j.neulet.2006.07.049

Genes

BDNF
GFAP
NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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