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Article

Molecular analysis of mitochondrial DNA point mutations by polymerase chain reaction.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006

Wong Lee-Jun C, Cobb Bryan R, Chen Tian-Jian

Abstract excerpt

Mitochondrial respiratory chain disorders are clinically and genetically heterogeneous. There are several mitochondrial DNA (mtDNA) point mutations responsible for common mitochondrial diseases such as mitochondrial encephalopathy, lactic acidosis, stroke-like events, myoclonic epilepsy and ragged red fibers, neuropathy, ataxia, retinitis pigmentosa, and Leber's hereditary optic neuropathy. As a result of the...

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PMID: 16916259
DOI: 10.1385/1-59745-074-X:135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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