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Article

THE SCN2A gene is not a likely candidate for familial mesial temporal lobe epilepsy.

Epilepsy research - 1 Oct 2006

Maurer-Morelli Cláudia Vianna, Secolin Rodrigo, Marchesini Rafael Breglio, Santos Neide Ferreira, Kobayashi Eliane, Cendes Fernando, Lopes-Cendes Iscia

Abstract excerpt

A transgenic mouse model carrying a mutation in the Scn2a gene showed chronic focal seizures associated with extensive cell loss and gliosis in the hippocampus, a similar phenotype found in familial mesial temporal lobe epilepsy (FMTLE). Our objective was to test whether the human homolog of the...

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Source

Identifiers

PMID: 16914293
DOI: 10.1016/j.eplepsyres.2006.06.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16914293-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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