Article
Isotachophoresis preconcentration integrated microfluidic chip for highly sensitive genotyping of the hepatitis B virus.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 21 Nov 2006
Liu Dayu, Shi Ming, Huang Huaiqing, Long Zhicheng, Zhou Xiaomian, Qin Jianhua, Lin Bingcheng
Abstract excerpt
The genotyping of hepatitis B virus (HBV) has become recently a valuable tool not only for epidemiological reasons but also for the clinical practice. Conventional methods for HBV genotyping typically include amplification of the target DNA sequences with a two-round nested PCR followed by separation of the amplified fragments by gel electrophoresis. A microfluidic chip that couples isotachophoresis (ITP)...
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