Article
Genomic DNA of leukemic patients: target for clinical diagnosis of MLL rearrangements.
Biotechnology journal - 1 Jun 2006
Meyer Claus, Kowarz Eric, Schneider Björn, Oehm Clarissa, Klingebiel Thomas, Dingermann Theo, Marschalek Rolf
Abstract excerpt
Genomic DNA is the optimal resource to analyze questions concerning genetic changes that are related to oncogenesis. This article tries to summarize recent efforts to analyze chromosomal changes that trigger the development of human acute myeloid and lymphoblastic leukemias. The aim of this study was to establish an universal method that enables the identification and characterization of chromosomal...
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