Article
Racial differences in the prevalence of Factor V Leiden mutation among patients on chronic warfarin therapy.
Blood cells, molecules & diseases - 1 Jan 2000
Limdi N A, Beasley T M, Allison D B, Rivers C A, Acton R T
Abstract excerpt
We report the prevalence of Factor V Leiden (FVL) in European American and African American patients on warfarin therapy residing in Alabama. METHODS.: Detailed history was obtained and FVL genotype was determined for 288 patients enrolled in a prospective cohort: Pharmacogenetic Optimization of Anticoagulation Therapy. Racial differences in genotype frequency were assessed by the Chi-square statistics and HWE...
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