Article
The Mel 14 antibody binds to the lectin domain of the murine peripheral lymph node homing receptor.
The Journal of cell biology - 1 Jan 1990
Bowen B R, Fennie C, Lasky L A
Abstract excerpt
Murine and human leukocytes express surface glycoproteins, termed homing receptors (HRs), containing lectin-like, EGF-like (egf), and complement binding-like domains, that apparently endow these cells with the ability to home to peripheral lymph nodes (pln's) by virtue of an adhesive interaction with the pln postcapillary venule endothelium. The murine pln HR was initially characterized with a rat monoclonal...
Topics
- Animals
- Antibodies, Monoclonal
- Antigen-Antibody Complex
- Antigens, Surface
- Chimera
- Chromosome Deletion
- Epitopes
- Humans
- Immunoglobulin G
- Lectins
- Lymph Nodes
- Mannans
