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Article

[The effect of CACNA1H gene G773D mutation on calcium channel function].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Aug 2006

Wang Ju-li, Han Chong-yang, Jing Yu-hong, Chen Yu-cai, Feng Nan, Lu Jian-jun, Zhang Yue-hua, Pan Hong, Wu Hu-sheng, Xu Ke-ming, Jiang Yu-wu, Liang Jian-min, Wang Ling, Wang Xiao-liang, Shen Yan, Wu Xi-ru

Abstract excerpt

OBJECTIVE: To study the effect of CACNA1H gene mutation G773D on calcium channel function. METHODS: By the overlap extension PCR we introduced G773D mutation into a human Cav3.2acDNA for constructing the mutant. And then using whole cell clamp technique, we studied the alterations of channel behavior in transfected HEK-293 cells. RESULTS: There were no difference in kinetics of activation and inactivation of...

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PMID: 16883519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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