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Article

[Pharmacogenetics of indirect anticoagulants: value of genotype for improvement of efficacy and safety of therapy].

Kardiologiia - 1 Jan 2006

Sychov D A, Kropacheva E S, Ignat'ev I V, Bulytova Iu M, Dobrovol'skiĭ A B, Panchenko E P, Kukes V G

Abstract excerpt

The review is devoted to the contemporary state of the problem of pharmacogenetics of indirect anticoagulants. At present there are data about effects of allele variants of CYP2C9, VKORC1, APOE genes on efficacy and safety of therapy with indirect anticoagulants. Detection of these variants is a perspective way to individualization of therapy with indirect anticoagulants.

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Topics

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Share to Anticoagulants
Share to Apolipoproteins E
Share to Aryl Hydrocarbon Hydroxylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biotransformation

Share to Cytochrome P-450 CYP2C9

Share to Mixed Function Oxygenases

Share to Pharmacogenetics

Share to Vitamin K Epoxide Reductases

Source

Identifiers

PMID: 16883270

Genes

APOE
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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