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Embryonic Stem Cell-Derived Endothelial Cells May Lack Complete Functional Maturation in vitro

1 Jan 2006

Abstract excerpt

Stem cell therapies will only become clinically relevant if the stem cells differentiated in vitro function as their in vivo counterparts. Here, we employed our previously developed techniques for deriving endothelial cells (>96% purity) from mouse embryonic stem cells (ESC) and compared these with mouse aortic endothelial cells (MAEC) obtained from thoracic aortas. Immunocytochemical analysis of ESC-derived...

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PMID: 16877873
DOI: 10.1159/000094791

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