Article
An autosomal dominant progressive congenital zonular nuclear cataract linked to chromosome 20p12.2-p11.23.
Molecular vision - 5 Dec 2006
Li Ningdong, Yang Yongjia, Bu Juan, Zhao Chen, Lu Shasha, Zhao Jun, Yan Li, Cui Lihong, Zheng Rongchang, Li Jianjun, Tang Jinsheng, Zhao Kanxing
Abstract excerpt
PURPOSE: To map and to identify the causal gene for autosomal dominant congenital cataract (ADCC) in a Chinese family. METHODS: A four-generation family with a history of progressive congenital cataracts was investigated. Twenty-three members of the family were examined ophthalmologically. Blood samples were collected from twenty-nine family members for genetic linkage analysis. Two-point LOD scores were...
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