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Article

A computer-based, image-analysis method to quantify HIV-1 infection in a single-cycle infectious center assay.

Journal of virological methods - 1 Oct 2006

Day John R, Martínez Laura E, Sásik Roman, Hitchin Douglas L, Dueck Megan E, Richman Douglas D, Guatelli John C

Abstract excerpt

Rapid and precise quantitation of the infectivity of HIV is important for molecular virologic studies as well as for measuring the activities of antiviral drugs and neutralizing antibodies. In the present study, an indicator cell line and image-analysis software were used to quantify HIV infectivity. Cells of the P4R5 line, which express the receptors for HIV infection as well as beta-galactosidase under the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16876264
DOI: 10.1016/j.jviromet.2006.06.019

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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