Article
Genetic diversity of enterovirus 71 associated with hand, foot and mouth disease epidemics in Japan from 1983 to 2003.
The Pediatric infectious disease journal - 1 Aug 2006
Hosoya Mitsuaki, Kawasaki Yukihiko, Sato Masatoki, Honzumi Ken, Kato Asako, Hiroshima Toyomasa, Ishiko Hiroaki, Suzuki Hitoshi
Abstract excerpt
BACKGROUND: Enterovirus 71 (EV71) is one of the major etiologic agents of hand, foot and mouth disease (HFMD). The surveillance data indicate that EV71 infection follows an epidemic mode of transmission, causing large outbreaks and then becoming quiescent for a few years. METHODS: We investigated the genetic diversity of a total of 121 EV71 strains isolated from patients with HFMD in Fukushima, Japan, from 1983...
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