Article
Change of major genotype of enterovirus 71 in outbreaks of hand-foot-and-mouth disease in Taiwan between 1998 and 2000.
Journal of clinical microbiology - 1 Jan 2002
Wang Jen-Ren, Tuan Yen-Chang, Tsai Huey-Pin, Yan Jing-Jou, Liu Ching-Chuan, Su Ih-Jen
Abstract excerpt
Two outbreaks of hand-foot-and-mouth disease (HFMD) occurred in Taiwan between 1998 and 2000. Enteroviruses were isolated from a total of 1,892 patients in this laboratory during this period. Of the virus isolates, enterovirus 71 (EV71) was diagnosed in 44.4% of the patients (132 of 297) in 1998, 2% (13 of 646) in 1999, and 20.5% (195 of 949) in 2000. Genetic analyses of the 5'-untranslated and VP1 regions of...
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