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Molecular Epidemiology and Evolution of Enterovirus 71 Strains Isolated from 1970 to 1998

1 Dec 1999

Abstract excerpt

Enterovirus 71 (EV71) (genus Enterovirus, family Picornaviridae), a common cause of hand, foot, and mouth disease (HFMD), may also cause severe neurological diseases, such as encephalitis and poliomyelitis-like paralysis. To examine the genetic diversity and rate of evolution of EV71, we have determined and analyzed complete VP1 sequences (891 nucleotides) for 113 EV71 strains isolated in the United States and...

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PMID: 10559310
DOI: 10.1128/jvi.73.12.9969-9975.1999

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