Article

The orthobunyavirus Gc glycoprotein head and stalk drives an infectious virion assembly pathway that is specific for the insect host

2025-11-19

Abstract excerpt

<h4>ABSTRACT</h4> The Orthobunyavirus genus of arthropod-borne segmented RNA viruses comprises several important pathogens including the human-infecting Oropouche virus and animal-infecting Schmallenberg virus (SBV). The prototypical Bunyamwera orthobunyavirus (BUNV) possesses envelope-embedded glycoprotein spikes, with Gc head and stalk domains forming distinctive tripods covering the envelope-proximal Gn. Spik...

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Literature Corpus work: 46dad047-c644-5483-962a-73c78c9b25f3
DOI: 10.1101/2025.11.18.689178

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